Volume 18, Issue 3 p. 264-266
Communication

Desmosterol in human milk

Richard M. Clark

Richard M. Clark

Department of Nutritional Sciences, University of Connecticut, Storrs, CT, 06268

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Mark B. Fey

Mark B. Fey

Department of Nutritional Sciences, University of Connecticut, Storrs, CT, 06268

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Robert G. Jensen

Robert G. Jensen

Department of Nutritional Sciences, University of Connecticut, Storrs, CT, 06268

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Dennis W. Hill

Dennis W. Hill

Microchemistry Laboratory, University of Connecticut, Storrs, CT, 06268

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First published: 01 March 1983
Citations: 25
To whom correspondence should be addressed.

Scientific Contribution No. 960, Storrs Agricultural Experiment Station, University of Connecticut, Storrs, CT 06268.

Abstract

Milk samples were collected from mothers at 2,6, 12 and 16 weeks postpartum. Desmosterol was found to be present in all the milk samples. Identification of desmosterol was based on retention times with two gas liquid chromatography (GLC) columns and verified by GC-m ass spectrometry. The concentration of desmosterol in breast milk increased significantly (P<0.5) from 0.6 mg/100 ml at 2 weeks to 1.3 mg/100 ml at 16 weeks postpartum. Desmosterol was not significantly correlated with total lipid, total cholesterol or free cholesterol in the milk.